Wu M, Jung L, Cooper AB, Fleet C, Chen C, Breault L, Clark K, Cai Z, Vincent S, Bottega S, Shen Q, Richardson A, Bosenburg M, Naber SP, DePinho RA, Kuperwasser C, Robinson MO. Tissue transgenic model of human breast cancer in mice. Proc. Natl. Acad. Sci 28;106(17):7022-7, 2009

DiMeo TA, Anderson K, Fen, C., Padkhe P, Naber S, Perou C., Kuperwasser C. A novel lung metastasis signature links wnt signaling with cancer cell self-renewal and the epithelial-mesenchymal transition in basal-like breast cancer. Cancer Research 69:5364-73, 2009.

Gupta, P.B., Onder, T.T., Jiang, G., Tao, K., Kuperwasser, C., Weinberg, R.A., Lander, E.S. Identification of selective inhibitors of cancer stem cells by high-throughput screening Cell 138(4):645-59, 2009.

Arendt LM, Rudnick JA, Keller PJ,Kuperwasser C#. Stroma in Breast Development and Disease. Seminars in Cellular Biology (in press) 2009 Oct 24. [Epub ahead of print]

Fillmore C, Kuperwasser C. Human breast cancer cell lines contain stem-like cells with the capacity to self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Research Mar 26;10(2):R25, 2008.

Maroulakou I, Oemler W, Naber SP, Klebba I, Kuperwasser C, Tsichlis P. Distinct roles of three Akt isoforms in lactogenic differentiation and involution. Journal of Cellular Physiology 217:468-477, 2008.

Christine Fillmore, Charlotte Kuperwasser Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man. Breast Cancer Research 2007;9(3):303., 2007.  Click here for text.  

 
Paulson KE, Rieger-Christ, K, McDevitt MA, Kuperwasser C, Kim J, Zhang X, Hu M, Berasi SP, Huang C, Paganelli, RH, Dilip Giri, MD; Seth Kauffman, MD; Joanne Blum, MD;Netto G, Huang Z, Wazer DE, Summerhayes IC, Yee AS. Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer, Cancer Research  67(13):6136-45.), 2007.

 
Thuy L. Phung, Godfred Eyiah-Mensah, Rebekah O’Donnell, Sharon Shechter, Kenneth Walsh, Charlotte Kuperwasser, Laura E. Benjamin. Endothelial Akt signaling is rate limiting for rapamycin inhibition of mouse mammary tumor progression. Cancer Research 67(11):5070-5, 2007.

 
Boutrus S., Hwu D., Chan, M,  Kuperwasser C., Lin C., Gerogakoudi I., A Portable Two-Color In Vivo Flow Cytometer for Real-Time Detection of Fluorescently-Labeled Circulating Cells, Journal of  Biomedical Optics Letters  12(2): e1-3, 2007.  Click here for text.

 
Gupta PB, Proia D, Weremowicz J, Naber S, Weinberg R, Kuperwasser C., Systemic stromal effects of estrogen promotes the growth of estrogen receptor-negative cancers, Cancer Research 67(5):2062-71, 2007.   Click here for text.


Piyush B. Gupta, Charlotte Kuperwasser, Contributions of estrogen to ER-negative breast tumor growth. Journal of Steriod Biochemistry & Molecular Biology, 102(1-5):71-8, 2006

 
            David Proia, Charlotte Kuperwasser. Reconstruction of human mammary tissues in a mouse model Nature 
            Protocols 1(1): 206-241, 2006.  Click here for text.

 
            Gupta, PB, Kuperwasser, C, Brunet, J-P.,  Ramaswamy, S.,   Naber, SP., Weinberg, RA. The melanocyte
            differentiation program predisposes for metastasis following neoplastic transformation, Nature Genetics                  
            37(10):1047-1054,2005.

DiMeo TA, Kuperwasser C., The evolving paradigm of tissue-specific metastasis. Breast Cancer Research 8:301-303, 2005.  Click here for text.

 
Charlotte Kuperwasser, Scott Dessain , Benjamin E. Bierbaum, Dan Garnet, Kara Sperandio, Stephan, Naber, Robert A. Weinberg, Michael Rosenblatt, A mouse model of human breast cancer metastasis to human bone, Cancer Research, 65:6130-6138,2005.  Click here for text.

Proia D, Kuperwasser C. Stroma: tumor agonist or antagonist, Cell Cycle 4(8): 1022-1025, 2005.

 
Gupta P.B., Kuperwasser C. Disease models of Breast cancer, Drug Discovery Today, 1: 9-16,2004.  Click here for text.

 
Charlotte Kuperwasser, Tony Chavarria, Min Wu,Greg Magrane, Joe W Gray, Loucinda Carey, Andrea Richardson,  Robert A. Weinberg, Reconstruction of functionally normal and malignant human breast tissues in mice, Proc. Natl. Acad. Sci, 101: 4966-4971, 2004.  Click here for text.

 
            Kuperwasser, C., Hurlbut, G.D., Kittrell, F.S., Dickenson, E., Laucirica, R., Medina , D., Naber, S.P., Jerry, D.J. 
            “Development of spontaneous mammary tumors in BALB/c p53-heterozygous mice: a model for Li-Fraumeni
            syndrome”. Am J            
            Pathol,157: 2151-2159, 2000.

 
            C. Kuperwasser, J. Pinkas, G.D. Hurlbut, S.P. Naber, D.J. Jerry. “Cytoplasmic sequestration and functional
            repression of p53 in the mammary epithelium is reversed by hormonal treatment”. Cancer Res, 60: 2723-2729, 2000.

 
            Jerry, D.J., Kittrell, F.S., Kuperwasser, C., Dickinson , E.S., Bonilla,  P.J., Butel, J.S., Medina , D., “A
            mammary-specific model demonstrates the role for the p53 tumor suppressor gene in tumor development”.
            Oncogene, 19: 1052-1058, 2000.

 
Jerry, D.J., Pinkas, J., Kuperwasser, C., Dickinson , E.S., Naber, S.P. “Regulation of the p53 tumor suppressor gene and its targets during involution”. J Mamm Biol Neo, 4: 177-181, 1999.

 
D.J. Jerry, C. Kuperwasser, S.R.Downing, J. Pinkas, C. He, E. Dickinson , S.Marconi, S.P. Naber. “Delayed involution of the mammary gland in BALB/c null mice”. Oncogene, 17: 2305-2312, 1998.

 
            D. Medina, L.C. Stephens, P.J. Bonilla, C.A. Hollmann, D. Schwahn, C. Kuperwasser, D.J. Jerry, J.S. Butel, R.E.
            Meyn. “Radiation-induced tumorigenesis in preneoplastic mouse mammary glands in vivo: significance of p53 status
            and apoptosis”. Mol Carcinogenesis, 22: 199-207, 1998.