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selected publications
Christine
Fillmore, Charlotte Kuperwasser
Human breast cancer stem cell markers CD44 and CD24: enriching for cells
with functional properties in mice or in man.
Breast Cancer Research 2007;9(3):303.,
2007. Click here for text.
Paulson KE, Rieger-Christ, K, McDevitt MA, Kuperwasser
C, Kim J, Zhang X, Hu M, Berasi SP, Huang C, Paganelli, RH, Dilip Giri, MD;
Seth Kauffman, MD; Joanne Blum, MD;Netto G, Huang Z, Wazer DE, Summerhayes IC,
Yee AS. Alterations of the HBP1 transcriptional repressor are associated with
invasive breast cancer, Cancer Research
67(13):6136-45.), 2007.
Thuy L. Phung, Godfred Eyiah-Mensah, Rebekah
O’Donnell, Sharon Shechter, Kenneth Walsh, Charlotte
Kuperwasser, Laura E. Benjamin. Endothelial
Akt signaling is rate limiting for rapamycin inhibition of mouse mammary tumor
progression. Cancer Research 67(11):5070-5, 2007.
Boutrus S., Hwu D., Chan, M,
Kuperwasser C., Lin C., Gerogakoudi I., A Portable Two-Color In
Vivo Flow Cytometer for Real-Time Detection of Fluorescently-Labeled
Circulating Cells, Journal of
Biomedical Optics Letters 12(2):
e1-3, 2007. Click here for
text.
Gupta PB, Proia D, Weremowicz J, Naber
S, Weinberg R, Kuperwasser C., Systemic stromal effects of estrogen
promotes the growth of estrogen receptor-negative cancers, Cancer Research
67(5):2062-71, 2007.
Click here for text.
Piyush B. Gupta, Charlotte Kuperwasser,
Contributions of estrogen to ER-negative breast tumor growth. Journal
of Steriod Biochemistry & Molecular Biology, 102(1-5):71-8, 2006
David
Proia, Charlotte Kuperwasser. Reconstruction of human mammary tissues in
a mouse model Nature
Protocols 1(1):
206-241, 2006. Click here for
text.
Gupta, PB, Kuperwasser, C, Brunet, J-P.,
Ramaswamy, S., Naber,
SP., Weinberg, RA. The melanocyte
differentiation program predisposes for metastasis following neoplastic
transformation, Nature Genetics
37(10):1047-1054,2005.
DiMeo TA, Kuperwasser C., The evolving paradigm of tissue-specific
metastasis. Breast Cancer Research 8:301-303, 2005. Click here
for text.
Charlotte Kuperwasser,
Scott Dessain , Benjamin E. Bierbaum, Dan Garnet, Kara Sperandio, Stephan, Naber,
Robert A. Weinberg, Michael Rosenblatt, A mouse model of human breast cancer
metastasis to human bone, Cancer Research, 65:6130-6138,2005.
Click here for text.
Proia D, Kuperwasser C. Stroma: tumor agonist or antagonist,
Cell Cycle 4(8): 1022-1025, 2005.
Gupta P.B., Kuperwasser C. Disease
models of Breast cancer, Drug Discovery Today, 1: 9-16,2004.
Click here for text.
Charlotte Kuperwasser,
Tony Chavarria, Min Wu,Greg Magrane, Joe W Gray, Loucinda Carey, Andrea
Richardson, Robert A. Weinberg,
Reconstruction of functionally normal and malignant human breast tissues in
mice, Proc. Natl. Acad. Sci,
101: 4966-4971, 2004. Click here
for text.
Kuperwasser,
C., Hurlbut, G.D., Kittrell, F.S.,
Dickenson, E., Laucirica, R.,
Medina
, D., Naber, S.P., Jerry, D.J.
“Development of spontaneous mammary tumors in BALB/c p53-heterozygous mice: a
model for Li-Fraumeni
syndrome”. Am
J
Pathol,157:
2151-2159, 2000.
C.
Kuperwasser, J. Pinkas, G.D. Hurlbut, S.P.
Naber, D.J. Jerry. “Cytoplasmic sequestration and functional
repression of
p53 in the mammary epithelium is reversed by hormonal treatment”. Cancer
Res, 60: 2723-2729, 2000.
Jerry,
D.J., Kittrell, F.S., Kuperwasser, C.,
Dickinson
, E.S., Bonilla, P.J., Butel, J.S.,
Medina
, D., “A
mammary-specific model demonstrates the role for the p53 tumor suppressor gene
in tumor development”.
Oncogene,
19: 1052-1058, 2000.
Jerry, D.J., Pinkas, J., Kuperwasser, C.,
Dickinson
, E.S., Naber, S.P. “Regulation of the p53 tumor suppressor gene and its
targets during involution”. J Mamm Biol Neo, 4: 177-181, 1999.
D.J. Jerry, C. Kuperwasser,
S.R.Downing, J. Pinkas, C. He,
E. Dickinson
, S.Marconi, S.P. Naber. “Delayed involution of the mammary gland in BALB/c
null mice”. Oncogene, 17: 2305-2312, 1998.
D.
Medina, L.C. Stephens, P.J. Bonilla, C.A. Hollmann, D. Schwahn, C.
Kuperwasser, D.J. Jerry, J.S. Butel, R.E.
Meyn.
“Radiation-induced tumorigenesis in preneoplastic mouse mammary glands in
vivo: significance of p53 status
and
apoptosis”. Mol Carcinogenesis, 22: 199-207, 1998.
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