selected publications

Christine Fillmore, Charlotte Kuperwasser Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man. Breast Cancer Research 2007;9(3):303., 2007.  Click here for text.

 
Paulson KE, Rieger-Christ, K, McDevitt MA, Kuperwasser C, Kim J, Zhang X, Hu M, Berasi SP, Huang C, Paganelli, RH, Dilip Giri, MD; Seth Kauffman, MD; Joanne Blum, MD;Netto G, Huang Z, Wazer DE, Summerhayes IC, Yee AS. Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer, Cancer Research  67(13):6136-45.), 2007.

 
Thuy L. Phung, Godfred Eyiah-Mensah, Rebekah O’Donnell, Sharon Shechter, Kenneth Walsh, Charlotte Kuperwasser, Laura E. Benjamin. Endothelial Akt signaling is rate limiting for rapamycin inhibition of mouse mammary tumor progression. Cancer Research 67(11):5070-5, 2007.

 
Boutrus S., Hwu D., Chan, M,  Kuperwasser C., Lin C., Gerogakoudi I., A Portable Two-Color In Vivo Flow Cytometer for Real-Time Detection of Fluorescently-Labeled Circulating Cells, Journal of  Biomedical Optics Letters  12(2): e1-3, 2007.  Click here for text.

 
Gupta PB, Proia D, Weremowicz J, Naber S, Weinberg R, Kuperwasser C., Systemic stromal effects of estrogen promotes the growth of estrogen receptor-negative cancers, Cancer Research 67(5):2062-71, 2007.   Click here for text.


Piyush B. Gupta, Charlotte Kuperwasser, Contributions of estrogen to ER-negative breast tumor growth. Journal of Steriod Biochemistry & Molecular Biology, 102(1-5):71-8, 2006

 
            David Proia, Charlotte Kuperwasser. Reconstruction of human mammary tissues in a mouse model Nature 
            Protocols
1(1): 206-241, 2006.  Click here for text.

 
            Gupta, PB, Kuperwasser, C, Brunet, J-P.,  Ramaswamy, S.,   Naber, SP., Weinberg, RA. The melanocyte
            differentiation program predisposes for metastasis following neoplastic transformation, Nature Genetics                  
            37(10):1047-1054,2005.


DiMeo TA, Kuperwasser C., The evolving paradigm of tissue-specific metastasis. Breast Cancer Research 8:301-303, 2005.  Click here for text.

 
Charlotte Kuperwasser, Scott Dessain , Benjamin E. Bierbaum, Dan Garnet, Kara Sperandio, Stephan, Naber, Robert A. Weinberg, Michael Rosenblatt, A mouse model of human breast cancer metastasis to human bone, Cancer Research, 65:6130-6138,2005.  Click here for text.


Proia D, Kuperwasser C.
Stroma: tumor agonist or antagonist, Cell Cycle 4(8): 1022-1025, 2005.

 
Gupta P.B., Kuperwasser C. Disease models of Breast cancer, Drug Discovery Today, 1: 9-16,2004.  Click here for text.

 
Charlotte Kuperwasser, Tony Chavarria, Min Wu,Greg Magrane, Joe W Gray, Loucinda Carey, Andrea Richardson,  Robert A. Weinberg, Reconstruction of functionally normal and malignant human breast tissues in mice, Proc. Natl. Acad. Sci, 101: 4966-4971, 2004.  Click here for text.

 
            Kuperwasser, C., Hurlbut, G.D., Kittrell, F.S., Dickenson, E., Laucirica, R., Medina , D., Naber, S.P., Jerry, D.J. 
            “Development of spontaneous mammary tumors in BALB/c p53-heterozygous mice: a model for Li-Fraumeni
            syndrome”. Am J            
            Pathol,157: 2151-2159, 2000.

 
            C. Kuperwasser, J. Pinkas, G.D. Hurlbut, S.P. Naber, D.J. Jerry. “Cytoplasmic sequestration and functional
            repression of p53 in the mammary epithelium is reversed by hormonal treatment”. Cancer Res, 60: 2723-2729, 2000.

 
            Jerry, D.J., Kittrell, F.S., Kuperwasser, C., Dickinson , E.S., Bonilla,  P.J., Butel, J.S., Medina , D., “A
            mammary-specific model demonstrates the role for the p53 tumor suppressor gene in tumor development”.
            Oncogene,
19: 1052-1058, 2000.

 
Jerry, D.J., Pinkas, J., Kuperwasser, C., Dickinson , E.S., Naber, S.P. “Regulation of the p53 tumor suppressor gene and its targets during involution”. J Mamm Biol Neo, 4: 177-181, 1999.

 
D.J. Jerry, C. Kuperwasser, S.R.Downing, J. Pinkas, C. He, E. Dickinson , S.Marconi, S.P. Naber. “Delayed involution of the mammary gland in BALB/c null mice”. Oncogene, 17: 2305-2312, 1998.

 
            D. Medina, L.C. Stephens, P.J. Bonilla, C.A. Hollmann, D. Schwahn, C. Kuperwasser, D.J. Jerry, J.S. Butel, R.E.
            Meyn. “Radiation-induced tumorigenesis in preneoplastic mouse mammary glands in vivo: significance of p53 status
            and apoptosis”. Mol Carcinogenesis, 22: 199-207, 1998.

 

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