Kissil, JL., Charest, A., New Tools for Dissecting RON Receptor Tyrosine Kinase Oncogenic Signaling. Cancer Biol Ther. 2006 Sep 11;5(9): In Press

Charest A., Wilker, EC., McLaughlin , ME. , Lane, K., Gowda, R., Coven, S., McMahon, K., Kovach, S., Feng, Y., Yaffe, MB., Jacks, T., Housman, D. ROS Fusion Tyrosine Kinase Activates a SHP-2/PI3K/mTOR Signaling Axis to Form Glioblastoma in Mice. Cancer Res, 2006, 66(15):7473-81. PubMed

McCarty, JH ., Lacy-Hulbert, A., Charest, A., Bronson, RT., Crowley, D., Housman , D., Savill , J., Roes, J., Hynes, RO. Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death. Development, 2005, 132(1):165-76. PubMed

Charest, A., Lane, K., McMahon, K., Park, J., Preisinger , E., Conroy, H., Housman , D. Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del ( 6)( q21q21 ). Genes Chromosomes Cancer, 2003, 37(1):58-71. PubMed

Charest, A., Kheifets , V., Park, J., Lane, K., McMahon, K., Nutt, C.L ., Housman , D. Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma. Proc Natl Acad Sci U S A., 2003, 100(3):916-21. PubMed

Jordan , B., Charest, A., Dowd, J.F ., Blumenstiel , J.P., Yeh , R.F ., Osman , A., Housman , D.E ., Landers, J.E . Genome complexity reduction for SNP genotyping analysis. Proc Natl Acad Sci U S A., 2002, 99(5):2942-7. PubMed

Charest, A., Lane, K., McMahon, K., Housman , D.E . Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N- ethylmaleimide -sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6. J Biol Chem. Aug 3; 2001, 276(31):29456-65. PubMed

Chattopadhyay , S., Kaul , R., Charest, A., Housman , D., Chen, J. SMAR1 , a novel, alternatively spliced gene product, binds the Scaffold/Matrix-associated region at the T cell receptor beta locus. Genomics. Aug 15; 2000, 68(1):93-6. PubMed

Storring , J.M ., Charest, A., Cheng, P., and Albert, P.R . TATA -driven Transcriptional Initiation and Regulation of the Rat Serotonin 5- HT 1A Receptor Gene. J Neurochem ., Jun 1999, 72(6):2238-47. PubMed

Angers- Loustau , A., Cote , J.F ., Charest, A., Dowbenko , D., Spencer, S., Lasky , L.A. , Tremblay, M.L . Protein Tyrosine Phosphatase-PEST Regulates Focal Adhesion Disassembly, Migration, and Cytokinesis in Fibroblasts. J Cell Biol , 1999, 144(5):1019-1031. PubMed

Cote , J.F ., Charest, A., Wagner, J., Tremblay, M.L . Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP - PEST as a model. Biochemistry, 1998, 37(38):13128-37. PubMed

 Heesen , M., Berman, M.A., Charest, A., Housman , D., Gerard, C., Dorf , M.E . Cloning and chromosomal mapping of an orphan chemokine receptor: mouse RDC1 . Immunogenetics , 1998, 47(5):364-70. PubMed

 Charest, A., Wagner, J., Kwan, M., and Tremblay, M.L . Coupling of the murine protein tyrosine phosphatase PEST to the epidermal growth factor ( EGF ) receptor through a Src homology 3 ( SH3 ) domain-mediated association with Grb2 . Oncogene 14: 1643-1651. PubMed

 Nguyen, L., Holgado-Madruga , M., Maroun , C., Fixman , E.D ., Kamikura , D., Fournier, T., Charest, A., Tremblay, M.L ., Wong, A.J ., Park, M. Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356. J Biol Chem , 1997, 272(33): 20811-20819. PubMed

 Charest, A., Wagner, J. , Jacob , S., McGlade , C.J ., and Tremblay, M.L . Phosphotyrosine Independent Binding of SHC to the NPLH Sequence of MPTP - PEST . Evidence for Extended PTB /PI Domain Recognition Specificity. J. Biol. Chem., 1996, 271 (14): 8424-8429. PubMed

 Albert, P.R ., Lembo , P., Storring , J., Charest, A., and Saucier, C. The 5- HT1A receptor: Signalling , Desensitization and Gene Transcription. Neuropsychopharmacology , 1996, 14: 19-25. PubMed

Charest, A., Wagner, J., Muise , E.S ., Heng , H.H.Q ., and Tremblay, M.L . 1995. Structure of the Murine MPTP - PEST Gene: Genomic Organization and Chromosomal Mapping.Genomics , 1995, 28 (3): 501-507. PubMed

Charest, A., Wagner, J., Shen , S.-H., and Tremblay, M.L . 1995. Murine Protein Tyrosine Phosphatase-PEST: a stable cytosolic protein tyrosine phosphatase. Biochem . J., 1995, 308 ( pt2 ): 425-32. PubMed

Charest, A., Wainer , B.H ., and Albert, P.R . 1993. Cloning and Differentiation-Induced Expression of a Murine Serotonin1A Receptor in a Septal Cell Line. 1993, J. Neuroscience 13: 5164-5171. PubMed