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Kissil, JL.,
Charest, A., New Tools for Dissecting RON Receptor Tyrosine Kinase Oncogenic
Signaling. Cancer Biol Ther. 2006 Sep 11;5(9): In Press
Charest A., Wilker, EC.,
McLaughlin
,
ME.
, Lane, K., Gowda, R., Coven, S., McMahon, K.,
Kovach, S., Feng, Y., Yaffe, MB., Jacks, T., Housman, D. ROS Fusion Tyrosine
Kinase Activates a SHP-2/PI3K/mTOR Signaling Axis to Form Glioblastoma in Mice.
Cancer Res, 2006, 66(15):7473-81. PubMed
McCarty,
JH ., Lacy-Hulbert, A., Charest, A., Bronson, RT., Crowley, D., Housman , D.,
Savill , J., Roes, J., Hynes, RO. Selective ablation of alphav integrins in the
central nervous system leads to cerebral hemorrhage, seizures, axonal
degeneration and premature death. Development, 2005, 132(1):165-76. PubMed
Charest, A., Lane, K., McMahon, K., Park, J., Preisinger , E., Conroy, H.,
Housman , D. Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma
with an interstitial
del
( 6)( q21q21 ). Genes Chromosomes Cancer, 2003,
37(1):58-71. PubMed
Charest, A., Kheifets , V., Park, J., Lane, K., McMahon, K., Nutt, C.L .,
Housman , D. Oncogenic targeting of an activated tyrosine kinase to the Golgi
apparatus in a glioblastoma. Proc Natl Acad Sci U S A., 2003, 100(3):916-21. PubMed
Jordan ,
B., Charest, A., Dowd, J.F ., Blumenstiel , J.P., Yeh , R.F ., Osman , A.,
Housman , D.E ., Landers, J.E . Genome complexity reduction for SNP genotyping
analysis. Proc Natl Acad Sci U S A., 2002, 99(5):2942-7. PubMed
Charest, A., Lane, K., McMahon, K., Housman , D.E . Association of a novel PDZ
domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-
ethylmaleimide -sensitive fusion protein (NSF) attachment protein receptor)
protein syntaxin 6. J Biol Chem. Aug 3; 2001, 276(31):29456-65. PubMed
Chattopadhyay
, S., Kaul , R., Charest, A., Housman , D., Chen, J. SMAR1 , a novel,
alternatively spliced gene product, binds the Scaffold/Matrix-associated region
at the T cell receptor beta locus. Genomics. Aug 15; 2000, 68(1):93-6. PubMed
Storring ,
J.M ., Charest, A., Cheng, P., and Albert, P.R . TATA -driven Transcriptional
Initiation and Regulation of the Rat Serotonin 5- HT 1A Receptor Gene. J
Neurochem ., Jun 1999, 72(6):2238-47. PubMed
Angers-
Loustau , A.,
Cote
, J.F ., Charest, A., Dowbenko
, D., Spencer, S., Lasky ,
L.A.
, Tremblay, M.L . Protein
Tyrosine Phosphatase-PEST Regulates Focal Adhesion Disassembly, Migration, and
Cytokinesis in Fibroblasts. J Cell Biol , 1999, 144(5):1019-1031. PubMed
Cote
, J.F ., Charest, A., Wagner,
J., Tremblay, M.L . Combination of gene targeting and substrate trapping to
identify substrates of protein tyrosine phosphatases using PTP -
PEST
as a model. Biochemistry,
1998, 37(38):13128-37. PubMed
Heesen , M., Berman, M.A., Charest, A., Housman , D., Gerard, C., Dorf ,
M.E . Cloning and chromosomal mapping of an orphan chemokine receptor: mouse
RDC1 . Immunogenetics , 1998, 47(5):364-70. PubMed
Charest, A., Wagner, J., Kwan, M., and Tremblay, M.L . Coupling of the
murine protein tyrosine phosphatase
PEST
to the epidermal growth factor
( EGF ) receptor through a Src homology 3 ( SH3 ) domain-mediated association
with Grb2 . Oncogene 14: 1643-1651. PubMed
Nguyen, L., Holgado-Madruga , M., Maroun , C., Fixman , E.D ., Kamikura ,
D., Fournier, T., Charest, A., Tremblay, M.L ., Wong, A.J ., Park, M.
Association of the multisubstrate docking protein Gab1 with the hepatocyte
growth factor receptor requires a functional Grb2 binding site involving
tyrosine 1356. J Biol Chem , 1997, 272(33): 20811-20819. PubMed
Charest, A., Wagner, J. , Jacob , S., McGlade , C.J ., and Tremblay, M.L .
Phosphotyrosine Independent Binding of SHC to the NPLH Sequence of MPTP -
PEST
. Evidence for Extended PTB /PI
Domain Recognition Specificity. J. Biol. Chem., 1996, 271 (14): 8424-8429. PubMed
Albert, P.R ., Lembo , P., Storring , J., Charest, A., and Saucier, C. The
5- HT1A receptor: Signalling , Desensitization and Gene Transcription.
Neuropsychopharmacology , 1996, 14: 19-25. PubMed
Charest, A., Wagner, J., Muise , E.S ., Heng , H.H.Q ., and Tremblay, M.L .
1995. Structure of the Murine MPTP -
PEST
Gene: Genomic Organization and Chromosomal Mapping.Genomics
, 1995, 28 (3): 501-507. PubMed
Charest,
A., Wagner, J., Shen , S.-H., and Tremblay, M.L . 1995. Murine Protein Tyrosine
Phosphatase-PEST: a stable cytosolic protein tyrosine phosphatase. Biochem . J.,
1995, 308 ( pt2 ): 425-32. PubMed
Charest, A., Wainer , B.H ., and Albert, P.R . 1993. Cloning and
Differentiation-Induced Expression of a Murine Serotonin1A Receptor in a Septal
Cell Line. 1993, J. Neuroscience 13: 5164-5171. PubMed
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