selected publications

Maroulakou IG, Oemler W, Naber SP, Tsichlis PN.  Akt1 ablation inhibits, whereas Akt2 ablation  accelerates, the development of mammary adenocarcinomas in Mouse Mammary Tumor Virus (MMTV)-ErbB2/Neu and Polyoma Middle T mice.  Cancer Res 2007; 67(1): 167-77.  (Corresponding Author)

 

Mao C, Tili  EG, Dose M, Haks MC, Bear SE, Maroulakou I, Horie K, Gaitanaris G, Ludwing T, Wiest DL, Gounari F, Tsichlis PN.   Unequal contribution of akt isoforms in the double-negative to double-positive thymocyte transition. J. Immunol. 2007 May 1;178(9):5443-53.

 

Tomczak MF, Gadjeva M, Wang YY, Brown K, Maroulakou I, Tsichlis PN, Erdman SE, Fox JG, Horwitz BH. Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus.  J Immunol. 2006 Jan 15;176(2):1244-51.

 

Bowe DB, Kenney NJ, Adereth Y, Maroulakou IG. Suppression of her2/neu mammary tumor growth in Cyclin D1-deficient mice is compensated for by cyclin E. Oncogene. 2002;21:291-298. (Corresponding Author)

 

Maroulakou IG, Bowe DB. Expression and function of Ets transcription factors in mammalian development:  A regulatory network.  Oncogene. 2000;19: 6432-6442. (Corresponding Author)

 

Maroulakou IG, Shibata M-A, Anver MR, Jorcyk C, Liu M-L, Roche N, Roberts A, Tsarfaty I, Resau J, Ward JM, Green JE. Heterotopic endochondral ossification associated with mixed tumor formation in C3(1)/Tag transgenic mice is associated with elevated TGF-betal a BMP-2 expression.  Oncogene. 1999;18(39):5435-5447.

 

Jorcyk C, Liu-M-L, Shibata M-A, Maroulakou IG, Komschlies K, McPhaul M, Resau J, Green JE.  Characterization of a tumorigenic murine prostate epithelial adenocarcinoma cell line: Morphologic alterations determined by the extracellular matrix.  Prostate. 1998;34(1):10-22.

 

Maroulakou I, Shibata M-A, Jorcyk CL, Chen XX, Green JE.  Reduced p53 dosage associated with mammary tumor metastases in C3(1)TAG transgenic mice.  Molecular Carcinogenesis. 1997;20:168-174.

 

Jorcyk CL, Garrett LJ, Maroulakou IG, Watson DK, Green JE.  Multiple    regulatory regions control the expression of the Ets-1 protooncogene in the developing mouse.  Cellular and Molecular Biol. 1997;43:211-225.

 

Shibata M-A, Maroulakou IG, Jorcyk CL, Gold LG, Ward JM, Green JE. p-53-independent apoptosis during mammary tumor progression in C3(1)/SV40 large T antigen transgenic mice:  Suppression of apoptosis during the transition from preneoplasia to carcinoma.  Cancer Res. 1996;56(13):2998-3003.

 

Kenney NJ, Smith GH, Maroulakou I, Johnson G, Gullick WJ, Green JE, Muller WJ, Merlino GH, Callahan R, Salomon DS, Dickson RB. Detection of amphiregulin and Cripto-1 in mammary tumors from transgenic mice. Molecular Carcinogenesis. 1996;15:44-56.

 

Byeon MK, Westerman M, Maroulakou IG, Henderson K, Suster S, Zhang X-K, Papas TS, Vesely J, Willingham M, Green JE, Schweinfest C.  The down-regulated in adenoma (DRA) gene encodes an intestine specific membrane glycoprotein.  Oncogene. 1996;12: 387-396.

 

Chen S-L, Maroulakou IG, Green JE, Romano-Spica V, Modi W, Lautenberger J, Bhat NK.  Isolation and characterization of a novel gene expressed in multiple cancers.  Oncogene. 1996;12:741-751.

 

Maroulakou IG, Pokholok DK, Cuprash DV, Alimzhanov MB, Kozlov SV, Novobrantseva TI, Turetskaya RL, Green JE, Nedospasov SA.  Cloning and in situ transcriptional analysis of the murine lymphotoxin-b (Ltb) gene.  Proc Natl Acad Sci USA. 1995;92:674-678(co-first author).

 

Maroulakou IG, Anver M, Garrett L, Green JE.  Prostate and breast cancer in transgenic mice carrying a rat C3(1) SV40 TAG fusion gene.  Proc Natl Acad Sci USA. 1994;91: 11236-11240.

 

Maroulakou IG, Papas TS, Green JE. Differential expression of ets-1 and ets-2 proto-oncogenes during murine embryogenesis.  Oncogene. 1994;9:  1551-1565.

 

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