stem cell transplant research laboratory
selected publications

Friedman R., Betancur M, Tuncer H, Boissel L. Klingemann, H. Umbilical cord mesenchymal stem cells: adjuvants for human cell transplantation, Biol Blood Marrow Transplant, 2007: 13: 1477-1486

Boissel. L, Tuncer HH, Betancur M, Wolfberg A, Klingemann H. Umbilical cord mesenchymal stem cells increase expansion of cord blood natural killer cells. Biol Blood Marrow Transplant 200814:1031-8

Muller T, Uherek C, Maki G, Chow KU, Schimpf A, Klingemann H, Tonn T, Wels WS. Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells.
Cancer Immunol Immunother  2008; 57: 411-23

Uherek C, Tonn T, Uherek B, Becker S, Schnierle B, Klingemann H, Wels W.

Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction.
Blood 2002;100:1265-73.

Boissel L, Betancur M, Wels WS, Tuncer H, Klingemann H. Transfection with mRNA for CD19 specific chimeric antigen receptor restores NK cell mediated killing of CLL cells.  Leuk Res 2009; 33:1255-9

Weitzman J, Boissel L, Rabinovitz A, Klein A, Klingemann H. Variable contribution of monoclonal antibodies to ADCC in CLL patients. Leuk Lymphoma, 2009;  26:1-8.

 

 

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